Using neuroimaging to help predict the onset of psychosis
نویسندگان
چکیده
The aim of this review is to assess the potential for neuroimaging measures to facilitate prediction of the onset of psychosis. Research in this field has mainly involved people at 'ultra-high risk' (UHR) of psychosis, who have a very high risk of developing a psychotic disorder within a few years of presentation to mental health services. The review details the key findings and developments in this area to date and examines the methodological and logistical challenges associated with making predictions in an individual subject in a clinical setting.
منابع مشابه
How can neuroimaging facilitate the diagnosis and stratification of patients with psychosis?
Early diagnosis and treatment of patients with psychosis are associated with improved outcome in terms of future functioning, symptoms and treatment response. Identifying neuroimaging biomarkers for illness onset and treatment response would lead to immediate clinical benefits. In this review we discuss if neuroimaging may be utilised to diagnose patients with psychosis, predict those who will ...
متن کاملTransition to psychosis associated with prefrontal and subcortical dysfunction in ultra high-risk individuals.
BACKGROUND People at ultra high risk (UHR) of psychosis have an elevated risk of developing a psychotic disorder, but it is difficult to predict which individuals will make a transition to frank illness. We investigated whether functional magnetic resonance imaging (fMRI) in conjunction with a phonological fluency task at presentation could distinguish subjects who subsequently developed psycho...
متن کاملتأخیر در درمان و مسیر مراجعه بیماران دچار پسیکوز بار اول
AbstractObjectives: The aim of this study was investigation the duration of untreated psychosis (DUP), associated factors and pathways to care among patients with first episode psychosis admitted to Roozbeh Hospital. Method: In this cross-sectional study, 91 patients with the diagnosis of first episode psychosis admitted to Roozbeh Hospital in Tehran, were assessed regarding the duration of unt...
متن کاملGray Matter Volumetric Abnormalities Associated with the Onset of Psychosis
Patients with psychosis display structural brain abnormalities in multiple brain regions. The disorder is characterized by a putative prodromal period called ultra-high-risk (UHR) status, which precedes the onset of full-blown psychotic symptoms. Recent studies on psychosis have focused on this period. Neuroimaging studies of UHR individuals for psychosis have revealed that the structural brain...
متن کاملAge of onset of schizophrenia: perspectives from structural neuroimaging studies.
Many of the major neuropsychiatric illnesses, including schizophrenia, have a typical age of onset in late adolescence. Late adolescence may reflect a critical period in brain development making it particularly vulnerable for the onset of psychopathology. Neuroimaging studies that focus on this age range may provide unique insights into the onset and course of psychosis. In this review, we exam...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- NeuroImage
دوره 145 Pt B شماره
صفحات -
تاریخ انتشار 2017